Cyclebase 3.0

Cell-cycle regulation database

GYP5 [YPL249C]

GTPase-activating protein (GAP) for yeast Rab family members; involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p; involved in recruiting Rvs167p to the bud tip during polarized growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; GYP5 has a paralog, GYL1, that arose from the whole genome duplication

Synonyms:  GYP5,  GYP5p,  Q12344,  Q12344p,  YPL249C ...

Linkouts:  STRING  UniProt