Cyclebase 3.0

Cell-cycle regulation database

ISU1 [YPL135W]

Conserved protein of the mitochondrial matrix; performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); ISU1 has a paralog, ISU2, that arose from the whole genome duplication; isu1 isu2 double mutant is inviable; human homolog ISCU implicated in mitochondrial myopathy, can complement isu1 isu2 double mutant; Belongs to the NifU family.

Synonyms:  ISU1,  ISU1p,  Q03020,  NUA1,  Q03020p ...

Linkouts:  STRING  UniProt