Cyclebase 3.0

Cell-cycle regulation database

MUK1 [YPL070W]

Protein MUK1; Guanine nucleotide exchange factor (GEF); involved in vesicle-mediated vacuolar transport, including Golgi-endosome trafficking and sorting through the multivesicular body (MVB); specifically stimulates the intrinsic guanine nucleotide exchange activity of Rab family members (Vps21p/Ypt52p/Ypt53p); partially redundant with GEF VPS9; required for localization of the CORVET complex to endosomes; contains a VPS9 domain

Synonyms:  MUK1,  MUK1p,  Q02866,  Q02866p,  YPL070W ...

Linkouts:  STRING  UniProt