Cyclebase 3.0

Cell-cycle regulation database

TOP1 [YOL006C]

Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination

Synonyms:  TOP1,  TOP1p,  TOP1_YEAST,  MAK1,  YOL006C ...

Linkouts:  UniProt