Cyclebase 3.0

Cell-cycle regulation database

NRD1 [YNL251C]

Protein NRD1; RNA-binding subunit of Nrd1 complex; complex interacts with exosome to mediate 3'-end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; interacts with CTD of RNA pol II large subunit Rpo21p at phosphorylated Ser5 to direct transcription termination of non-polyadenylated transcripts; H3K4 trimethylation of transcribed regions by Set1p enhances recruitment of Nrd1p to those sites; role in regulation of mitochondrial abundance and cell size

Synonyms:  NRD1p,  P53617,  N0868,  P53617p,  YNL251C ...

Linkouts:  STRING  UniProt