Cyclebase 3.0

Cell-cycle regulation database

ASI3 [YNL008C]

Amino acid sensor-independent protein 3; Subunit of the inner nuclear membrane Asi ubiquitin ligase complex; Asi complex targets both misfolded proteins of the inner nuclear membrane-associated degradation (INMAD) pathway and regulators of sterol biosynthesis for ubiquitin-mediated degradation; acts with Asi1p and Asi2p to ensure the fidelity of SPS-sensor signaling by targeting latent unprocessed forms of Stp1p and Stp2p, maintaining the repressed state of gene expression in the absence of inducing amino acids

Synonyms:  ASI3,  ASI3p,  P53983,  N2874,  P53983p ...

Linkouts:  STRING  UniProt