Cyclebase 3.0

Cell-cycle regulation database

CUE1 [YMR264W]

Coupling of ubiquitin conjugation to ER degradation protein 1; Ubiquitin-binding protein; ER membrane protein that recruits and integrates the ubiquitin-conjugating enzyme Ubc7p into ER membrane-bound ubiquitin ligase complexes that function in the ER-associated degradation (ERAD) pathway for misfolded proteins; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination and to promote diubiquitin elongation, facilitating polyubiquitin chain formation

Synonyms:  CUE1,  CUE1p,  P38428,  KIS4,  P38428p ...

Linkouts:  STRING  UniProt