Cyclebase 3.0

Cell-cycle regulation database

COA6 [YMR244C-A]

Protein involved in cytochrome c oxidase (Complex IV) assembly; involved in delivery of copper to Complex IV; also required for efficient formation of respiratory supercomplexes comprised of Complexes III and IV; localizes to the mitochondrial intermembrane space; ortholog implicated in cardiac defects in zebrafish and human; transcription is induced in response to the DNA-damaging agent MMS; protein abundance increases in response to DNA replication stress

Synonyms:  COA6,  COA6p,  YMR244C-A,  Q3E846,  YMR244C-Ap ...

Linkouts:  STRING  UniProt