Cyclebase 3.0

Cell-cycle regulation database

GUA1 [YMR217W]

GMP synthase; highly conserved enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation; reduction-of-function mutation gua1-G388D causes changes in cellular guanine nucleotide pools, defects in general protein synthesis, and impaired translation of GCN4 mRNA

Synonyms:  GUA1,  GUA1p,  P38625,  P38625p,  YM8261.11 ...

Linkouts:  STRING  UniProt