Cyclebase 3.0

Cell-cycle regulation database

YAP1 [YML007W]

Pleiotropic drug resistance protein PDR4; Basic leucine zipper (bZIP) transcription factor; required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; Yap1p is degraded in the nucleus after the oxidative stress has passed; mediates resistance to cadmium; relative distribution to the nucleus increases upon DNA replication stress; YAP1 has a paralog, CAD1, that arose from the whole genome duplication

Synonyms:  YAP1,  YAP1p,  P19880,  P19880p,  PAR1 ...

Linkouts:  STRING  UniProt