Cyclebase 3.0

Cell-cycle regulation database

GCD7 [YLR291C]

Beta subunit of the translation initiation factor eIF2B; the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; human homolog EIF2B2 can complement yeast mutant, allows growth down-regulation of yeast gene; Belongs to the eIF-2B alpha/beta/delta subunits family.

Synonyms:  GCD7,  GCD7p,  P32502,  L8003.17,  P32502p ...

Linkouts:  STRING  UniProt