Cyclebase 3.0

Cell-cycle regulation database

GCN3 [YKR026C]

Alpha subunit of translation initiation factor eIF2B; guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; positive regulator of GCN4 expression; assembles into filaments with Gcd2p, Gcd6p, Gcd7p, and Sui2p as cells approach stationary phase and under cytosolic acidification and starvation conditions; human homolog EIF2B1 can complement yeast null mutant; Belongs to the eIF-2B alpha/beta/delta subunits family.

Synonyms:  GCN3,  GCN3p,  P14741,  AAS2,  P14741p ...

Linkouts:  STRING  UniProt