Cyclebase 3.0

Cell-cycle regulation database

RRN3 [YKL125W]

Protein required for transcription of rDNA by RNA polymerase I; transcription factor independent of DNA template; involved in recruitment of RNA polymerase I to rDNA; structure reveals unique HEAT repeat fold and a surface serine patch; phosphorylation of serine patch impairs cell growth and reduces RNA polymerase I binding in vitro and RNA polymerase I recruitment to the rDNA gene in vivo; Belongs to the RRN3 family.

Synonyms:  RRN3,  RRN3p,  P36070,  P36070p,  YKL125W ...

Linkouts:  STRING  UniProt