Cyclebase 3.0

Cell-cycle regulation database

BIR1 [YJR089W]

Protein BIR1; Subunit of chromosomal passenger complex (CPC); CPC is comprised of Ipl1p-Sli15p-Bir1p-Nbl1p and regulates chromosome segregation; required for chromosome bi-orientation and for spindle assembly checkpoint activation upon reduced sister kinetochore tension; relative distribution to shortened microtubules increases upon DNA replication stress; sumoylated in an Mms21p-dependent manner; human survivin homolog

Synonyms:  BIR1,  BIR1p,  P47134,  J1880,  P47134p ...

Linkouts:  STRING  UniProt