Cyclebase 3.0

Cell-cycle regulation database

ASF1 [YJL115W]

Anti-silencing function protein 1; Nucleosome assembly factor; involved in chromatin assembly, disassembly; required for recovery after DSB repair; role in H3K56 acetylation required for expression homeostasis, buffering mRNA synthesis rate against gene dosage changes in S phase; anti-silencing protein, derepresses silent loci when overexpressed; role in regulating Ty1 transposition; relocalizes to cytosol under hypoxia; growth defect of asf1 null is functionally complemented by either human ASF1A or ASF1B

Synonyms:  ASF1,  ASF1p,  P32447,  CIA1,  J0755 ...

Linkouts:  STRING  UniProt