Cyclebase 3.0

Cell-cycle regulation database

SRS2 [YJL092W]

DNA helicase and DNA-dependent ATPase; involved in DNA repair and checkpoint recovery, needed for proper timing of commitment to meiotic recombination and transition from Meiosis I to II; blocks trinucleotide repeat expansion; affects genome stability; disassembles Rad51p nucleoprotein filaments during meiotic recombination; stimulates activity of the Mus81p-Mms4p endonuclease, independently of Srs2p catalytic activity; functional homolog of human RTEL1

Synonyms:  SRS2,  SRS2p,  P12954,  HPR5,  J0913 ...

Linkouts:  STRING  UniProt