Cyclebase 3.0

Cell-cycle regulation database

DPB11 [YJL090C]

Replication initiation protein that loads DNA pol epsilon onto pre-replication complexes at origins; checkpoint sensor recruited to stalled replication forks by the checkpoint clamp complex where it activates Mec1p; ortholog of human TopBP1

Synonyms:  DPB11,  DPB11p,  DPB11_YEAST,  J0918,  YJL090C ...

Linkouts:  UniProt