Cyclebase 3.0

Cell-cycle regulation database

HXK2 [YGL253W]

Hexokinase isoenzyme 2; phosphorylates glucose in cytosol; predominant hexokinase during growth on glucose; represses expression of HXK1, GLK1, induces expression of its own gene; antiapoptotic; phosphorylation/dephosphorylation at Ser14 by kinase Snf1p, phosphatase Glc7p-Reg1p regulates nucleocytoplasmic shuttling of Hxk2p; functions downstream of Sit4p in control of cell cycle, mitochondrial function, oxidative stress resistance, chronological lifespan; has paralog HXK1

Synonyms:  HXK2,  HXK2p,  P04807,  HEX1,  HKB ...

Linkouts:  STRING  UniProt