Cyclebase 3.0

Cell-cycle regulation database

CDH1 [YGL003C]

Activator of anaphase-promoting complex/cyclosome (APC/C); antagonist of the spindle assembly checkpoint; directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including: Cdc20p, Ase1p, Cin8p, Fin1p and Clb5p; partially active in metaphase, and fully active in anaphase; cell-cycle regulated; Belongs to the WD repeat CDC20/Fizzy family.

Synonyms:  CDH1,  CDH1p,  P53197,  HCT1,  P53197p ...

Linkouts:  STRING  UniProt