Cyclebase 3.0

Cell-cycle regulation database

RNR1 [YER070W]

Ribonucleoside-diphosphate reductase large chain 1; Major isoform of large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits; relative distribution to the nucleus increases upon DNA replication stress; RNR1 has a paralog, RNR3, that arose from the whole genome duplication

Synonyms:  RNR1,  RNR1p,  P21524,  CRT7,  P21524p ...

Linkouts:  STRING  UniProt