Cyclebase 3.0

Cell-cycle regulation database

MOT2 [YER068W]

General negative regulator of transcription subunit 4; Ubiquitin-protein ligase subunit of the CCR4-NOT complex; with Ubc4p, ubiquitinates nascent polypeptide-associated complex subunits and histone demethyase Jhd2p; CCR4-NOT has roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication

Synonyms:  MOT2,  MOT2p,  P34909,  CCL1,  NOT4 ...

Linkouts:  STRING  UniProt