Cyclebase 3.0

Cell-cycle regulation database

SRB4 [YER022W]

Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; homozygosity of the human MED17 L371P mutation is associated with infanti /.../ebral and cerebellar atrophy with poor myelination

Synonyms:  SRB4,  SRB4p,  MED17_YEAST,  MED17,  YER022W ...

Linkouts:  UniProt