Cyclebase 3.0

Cell-cycle regulation database

HSP31 [YDR533C]

Glutathione-independent glyoxalase HSP31; Methylglyoxalase that converts methylglyoxal to D-lactate; involved in oxidative stress resistance, diauxic shift, and stationary phase survival; has similarity to E. coli Hsp31 and C. albicans Glx3p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease and cancer; exists as a dimer and contains a putative metal-binding site; protein abundance increases in response to DNA replication stress; Belongs to the peptidase C56 family. HSP31-like subfamily.

Synonyms:  HSP31,  HSP31p,  Q04432,  D9719.36,  Q04432p ...

Linkouts:  STRING  UniProt