Cyclebase 3.0

Cell-cycle regulation database

DOA4 [YDR069C]

Ubiquitin-specific-processing protease 4; Ubiquitin hydrolase; deubiquitinates intralumenal vesicle (ILVs) cargo proteins; required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins destined for the vacuole; DOA4 has a paralog, UBP5, that arose from the whole genome duplication; Belongs to the peptidase C19 family.

Synonyms:  DOA4,  DOA4p,  P32571,  D4270,  DOS1 ...

Linkouts:  STRING  UniProt