Cyclebase 3.0

Cell-cycle regulation database

TPI1 [YDR050C]

Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region; inhibition of Tpi1p activity by PEP (phosphoenolpyruvate) stimulates redox metabolism in respiring cells; E104D mutation in human homolog TPI1 causes a rare autosomal disease; human TPI1 can complement yeast null mutant

Synonyms:  TPI1,  TPI1p,  P00942,  P00942p,  YD9609.05C ...

Linkouts:  STRING  UniProt