Cyclebase 3.0

Cell-cycle regulation database

MPS1 [YDL028C]

Regulatory cell proliferation kinase 1; Dual-specificity kinase; autophosphorylation required for function; required for spindle pole body (SPB) duplication and spindle checkpoint function; contributes to bi-orientation by promoting formation of force-generating kinetochore-microtubule attachments in meiosis I; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, kinetochore protein Cnn1p, and checkpoint protein Mad1p; substrate of APCC(Cdh1); similar to human Mps1p

Synonyms:  MPS1,  MPS1p,  P54199,  D2785,  P54199p ...

Linkouts:  STRING  UniProt