Cyclebase 3.0

Cell-cycle regulation database

PDI1 [YCL043C]

Protein disulfide isomerase; multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds; forms a complex with Mnl /.../t has exomannosidase activity, processing unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2 which promotes degradation in the unfolded protein response

Synonyms:  PDI1,  PDI1p,  PDI_YEAST,  MFP1,  TRG1 ...

Linkouts:  UniProt