Cyclebase 3.0

Cell-cycle regulation database

ATG12 [YBR217W]

Autophagy-related protein 12; Ubiquitin-like modifier involved in autophagy and the Cvt pathway; conserved; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3p by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation

Synonyms:  ATG12,  ATG12p,  P38316,  APG12,  P38316p ...

Linkouts:  STRING  UniProt