Cyclebase 3.0

Cell-cycle regulation database

AME1 [YBR211C]

Essential kinetochore protein associated with microtubules and SPBs; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p); involved in spindle checkpoint maintenance; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-U and fission yeast Mis17; relative distribution to the nucleus increases upon DNA replication stress

Synonyms:  AME1,  AME1p,  P38313,  ARP100,  P38313p ...

Linkouts:  STRING  UniProt