Cyclebase 3.0

Cell-cycle regulation database

SKI3 [YPR189W]

Superkiller protein 3; Ski complex component and TPR protein; mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay; mutations in the human ortholog, TTC37, causes Syndromic diarrhea/Trichohepatoenteric (SD/THE) syndrome

Synonyms:  SKI3,  SKI3p,  P17883,  P17883p,  P9677.7 ...

Linkouts:  STRING  UniProt