Cyclebase 3.0

Cell-cycle regulation database

ROX1 [YPR065W]

Heme-dependent repression factor; Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance

Synonyms:  ROX1,  ROX1p,  P25042,  P25042p,  YP9499.20 ...

Linkouts:  STRING  UniProt