Cyclebase 3.0

Cell-cycle regulation database

YME1 [YPR024W]

Catalytic subunit of i-AAA protease complex; complex is located in mitochondrial inner membrane; responsible for degradation of unfolded or misfolded mitochondrial gene products; serves as nonconventional translocation motor to pull PNPase into intermembrane space; also has role in intermembrane space protein folding; mutation causes elevated rate of mitochondrial turnover; human homolog YME1L1 can complement yeast null mutant; In the C-terminal section; belongs to the peptidase M41 family.

Synonyms:  YME1,  YME1p,  P32795,  OSD1,  P32795p ...

Linkouts:  STRING  UniProt