Cyclebase 3.0

Cell-cycle regulation database

HSP82 [YPL240C]

Heat shock protein Hsp90 heat-inducible isoform; Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; contains two acid-rich unstructured regions that promote solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication

Synonyms:  HSP82,  HSP82p,  P02829,  HSP90,  P02829p ...

Linkouts:  STRING  UniProt