Cyclebase 3.0

Cell-cycle regulation database

CET1 [YPL228W]

RNA 5'-triphosphatase involved in mRNA 5' capping; subunit of mRNA capping enzyme, which is a heterotetramer composed of a Cet1p homodimer and two molecules of guanylyltransferase Ceg1p; Cet1p also has a role in regulation of RNAPII pausing at promoter-proximal sites; interaction between Cet1p and Ceg1p is required for Ceg1p nuclear import; mammalian enzyme is single bifunctional polypeptide; human homolog RNGTT can complement yeast cet1 null mutant

Synonyms:  CET1,  CET1p,  O13297,  O13297p,  P1433 ...

Linkouts:  STRING  UniProt