SAR1 [YPL218W]
Secretion-associated RAS-related protein 1; ARF family GTPase; component of the COPII vesicle coat; required for transport vesicle formation during ER to Golgi protein transport; lowers membrane rigidity aiding vesicle formation; localizes to ER-mitochondrial contact sites where it enhances membrane curvature, thereby reducing contact size via its N-terminal amphipathic helix; regulates mitochondrial fission and fusion dynamics
Synonyms: SAR1, SAR1p, P20606, P20606p, YPL218W ...