Cyclebase 3.0

Cell-cycle regulation database

NAB3 [YPL190C]

RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p); complex interacts with exosome to mediate 3'-end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; required for termination of non-poly(A) transcripts and efficient splicing; Nrd1-Nab3 pathway appears to have a role in rapid suppression of some genes when cells are shifted to poor growth conditions, indicating role for Nrd1-Nab3 in regulating cellular response to nutrient availability

Synonyms:  NAB3,  NAB3p,  P38996,  HMD1,  P38996p ...

Linkouts:  STRING  UniProt