Cyclebase 3.0

Cell-cycle regulation database

CUP9 [YPL177C]

Homeobox protein CUP9; Homeodomain-containing transcriptional repressor; regulates expression of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription; CUP9 has a paralog, TOS8, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress

Synonyms:  CUP9,  CUP9p,  P41817,  P41817p,  YPL177C ...

Linkouts:  STRING  UniProt