Cyclebase 3.0

Cell-cycle regulation database

AIM44 [YPL158C]

Altered inheritance of mitochondria protein 44; Protein that regulates Cdc42p and Rho1p; functions in the late steps of cytokinesis and cell separation; sustains Rho1p at the cell division site after actomyosin ring contraction; inhibits the activation of Cdc42-Cla4 at the cell division site to prevent budding inside the old bud neck; transcription is regulated by Swi5p; null mutant displays elevated frequency of mitochondrial genome loss; relocalizes from bud neck to cytoplasm upon DNA replication stress

Synonyms:  AIM44,  AIM44p,  Q99299,  P2570,  Q99299p ...

Linkouts:  STRING  UniProt