UME1 [YPL139C]
WD repeat-containing transcriptional modulator 3; Component of both the Rpd3S and Rpd3L histone deacetylase complexes; negative regulator of meiosis; required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p; UME1 has a paralog, WTM2, that arose from the whole genome duplication
Synonyms: UME1, UME1p, Q03010, LPI7C, Q03010p ...