Cyclebase 3.0

Cell-cycle regulation database

CIP1 [YPL014W]

Uncharacterized protein YPL014W; Cyclin-dependent kinase inhibitor; interacts with and inhibits the Cdc28p/Cln2p, G1/S phase cyclin-dependent kinase complex but not S-phase, or M-phase complexes; overexpression blocks cells in G1 phase and stabilizes the Cdc28p inhibitor Sic1p, while disruption accelerates the G1/S phase transition; phosphorylated during S phase in a Cdc28p-dependent manner; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus

Synonyms:  CIP1,  CIP1p,  YPL014W,  Q02606,  YPL014Wp ...

Linkouts:  STRING  UniProt