Cyclebase 3.0

Cell-cycle regulation database

RQC2 [YPL009C]

Ribosome quality control complex subunit 2; Component of RQC, which mediates nascent chain degradation; RQC (ribosome quality control complex) is a ribosome-bound complex required for degradation of polypeptides arising from stalled translation; recruits alanine- and threonine-charged tRNA to the A site and directs the elongation of nascent chains independently of mRNA or 40S subunits; monitors translation stress and signals this to Hsf1p; Belongs to the NEMF family.

Synonyms:  RQC2,  RQC2p,  TAE2,  Q12532,  TAE2p ...

Linkouts:  STRING  UniProt