Cyclebase 3.0

Cell-cycle regulation database

CHL1 [YPL008W]

Chromosome transmission fidelity protein 1; Probable DNA helicase; involved in sister-chromatid cohesion and genome integrity and interstrand cross-link repair; interacts with ECO1 and CTF18; mutants are defective in silencing, rDNA recombination, aging and the heat shock response; FANCJ-like helicase family member; mutations in the human homolog, DDX11/ChLR1, cause Warsaw breakage syndrome; Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.

Synonyms:  CHL1,  CHL1p,  P22516,  CTF1,  P22516p ...

Linkouts:  STRING  UniProt