Cyclebase 3.0

Cell-cycle regulation database

HEM4 [YOR278W]

Hydroxymethylbilane hydrolyase [cyclizing]; Uroporphyrinogen III synthase; catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in heme biosynthesis; deficiency in the human homolog can result in the disease congenital erythropoietic porphyria

Synonyms:  HEM4,  HEM4p,  P06174,  O5463,  ORF1 ...

Linkouts:  STRING  UniProt