Cyclebase 3.0

Cell-cycle regulation database

MOD5 [YOR274W]

Isopentenyl-diphosphate: tRNA isopentenyltransferase; Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase; required for biosynthesis of isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; also has a role in tRNA gene-mediated silencing; gene encodes two isozymic forms; converts to a prion form, prion conversion contributes to azole antifungal resistance by upregulating ergosterol biosynthesis; homolog of human TRIT1, a mutation in which is associated with severe combined respiratory chain defects

Synonyms:  MOD5,  MOD5p,  P07884,  P07884p,  YOR274W ...

Linkouts:  STRING  UniProt