Cyclebase 3.0

Cell-cycle regulation database

APC5 [YOR249C]

Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C); APC/C is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; component of the platform domain of the APC/C, based on structural analysis; relative distribution to nuclear foci decreases upon DNA replication stress; Belongs to the APC5 family.

Synonyms:  APC5,  APC5p,  Q08683,  Q08683p,  RMC1 ...

Linkouts:  STRING  UniProt