Cyclebase 3.0

Cell-cycle regulation database

DED1 [YOR204W]

ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase; required for translation initiation of all yeast mRNAs; binds to mRNA cap-associated factors, and binding stimulates Ded1p RNA-dependent ATPase activity; mutation in human homolog DBY is associated with male infertility; human homolog DDX3X complements ded1 null mutation; DED1 has a paralog, DBP1, that arose from the whole genome duplication

Synonyms:  DED1,  DED1p,  P06634,  P06634p,  SPP81 ...

Linkouts:  STRING  UniProt