Cyclebase 3.0

Cell-cycle regulation database

WHI5 [YOR083W]

G1-specific transcriptional repressor WHI5; Repressor of G1 transcription; binds to SCB binding factor (SBF) at SCB target promoters in early G1; dilution of Whi5p concentration during cell growth determines cell size; phosphorylation of Whi5p by the CDK, Cln3p/Cdc28p relieves repression and promoter binding by Whi5, and contributes to both the determination of critical cell size at START and cell fate; periodically expressed in G1; Belongs to the WHI5/NRM1 family.

Synonyms:  WHI5,  WHI5p,  Q12416,  Q12416p,  YOR083W ...

Linkouts:  STRING  UniProt