Cyclebase 3.0

Cell-cycle regulation database

SKI7 [YOR076C]

Superkiller protein 7; GTP-binding protein that couples the Ski complex and exosome; putative pseudo-translational GTPase involved in 3'-to-5' mRNA decay pathway; interacts with both the cytoplasmic exosome and the Ski complex; eRF3-like domain targets nonstop mRNA for degradation; null mutants have a superkiller phenotype; SKI7 has a paralog, HBS1, that arose from the whole genome duplication; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family.

Synonyms:  SKI7,  SKI7p,  Q08491,  Q08491p,  YOR076C ...

Linkouts:  STRING  UniProt