Cyclebase 3.0

Cell-cycle regulation database

SGO1 [YOR073W]

Shugoshin; Component of the spindle checkpoint; involved in sensing lack of tension on mitotic chromosomes; protects centromeric Rec8p at meiosis I; required for accurate chromosomal segregation at meiosis II and for mitotic chromosome stability; recruits condensin to the pericentric region of chromosomes during meiosis; dissociates from pericentromeres when sister kinetochores are under tension; Belongs to the shugoshin family.

Synonyms:  SGO1,  SGO1p,  Q08490,  Q08490p,  YOR073W ...

Linkouts:  STRING  UniProt