Cyclebase 3.0

Cell-cycle regulation database

NOB1 [YOR056C]

20S-pre-rRNA D-site endonuclease NOB1; Protein involved in proteasomal and 40S ribosomal subunit biogenesis; required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA; cleavage is activated by Fun12p, a GTPase and translation initiation factor; relocalizes from nucleus to nucleolus upon DNA replication stress; Belongs to the NOB1 family.

Synonyms:  NOB1,  NOB1p,  Q08444,  Q08444p,  YOR056C ...

Linkouts:  STRING  UniProt